c 1475 BCE- Miriam, the elder sister of Moses and Aaron, was afflicted with tzaraat, after speaking negatively of Moses, and was quarantined outside of the camp for seven days--as mentioned in Numbers 12. Others cite tomorrow 23 Sivan as the date Miriam was afflicted with tzaraat.
1525- The Pope orders Jews of Carpentras, France, to wear distinctive yellow hats.